![]() ![]() ![]() In seeking a definition both useful and accessible to the lay public, the participants proposed simply that, ‘Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.’ Even more significant for emergency response and treatment, the participants established a set of three diagnostic criteria for anaphylaxis to include observations of skin and mucosal tissue symptoms, respiratory distress, reduced blood pressure, and/or gastrointestinal symptoms over a time course of minutes to hours after exposure to allergen. The outcomes of these symposia were published in two reports in the Journal of Allergy and Clinical Immunology. With the initiative of the National Institute of Allergy and Infectious Diseases and the Food Allergy and Anaphylaxis Network, representatives from several organizations in the United States and abroad met in symposia in 20 to debate and seek consensus on a universally accepted definition and clinical criteria for identification of anaphylaxis.
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